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Ayurveda formulation from single herb being developed to treat under NMITLI

12 January 2011

NEW DELHI: Under New Millennium Indian Technology Leadership Initiative (NMITLI) scheme of CSIR, an Auyrveda based formulation comprising single herb has been developed using reverse pharmacology approach as adjuvant to anti-hyperglycemics like metformin, in the run-up to develop cost-effective drug to treat diabetes.

According to the sources in the Department of Science and Technology, the formulation has been scientifically validated through pre-clinical, clinical phase I, phase II A & phase II B and limited phase III multi-centric clinical studies in patients uncontrolled on existing drugs such as sulphonylurea and metformin, thus decreasing the dosage requirement of existing drugs.

In another NMITLI project, oral delivery of insulin is being attempted. During current XI Five Year Plan, CSIR laboratories have undertaken a programme on “Diabetes mellitus-new drug discovery R&D, molecular mechanisms and genetic factors”. The objective of the programme is to design, synthesise, isolation and development of new therapeutic agents from natural sources for type II diabetes. The programme also aims at elucidation of mechanism of action of promising agents, genetic, epigenetic and proteomic basis of the disease and identification of biomarkers and mechanism of disease progression.

“The project is progressing well. But it will take some more time to launch the drug in the markets,” sources said. The information on progress of the ongoing projects aimed at developing drug to treat diabetes have been collected by the Department following a query from the Parliamentary Panel attached to the Ministry of Science and Technology……

Read more: http://www.pharmabiz.com/article/detnews.asp?articleid=59293&sectionid=

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Written by csirindia

January 12, 2011 at 4:55 pm

Posted in CSIR

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